Fluo-8 No Wash Calcium Assay Kit

Business Type
Manufacturer
Country
USA
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Product Detail

Fluo-8 No Wash Calcium Assay Kit is a fluorescence-based assay for detecting intracellular calcium mobilization. Cells expressing a GPCR of interest that signals through calcium are pre-loaded with Fluo-8 which can cross the cell membrane. Once inside the cell, the lipophilic blocking groups of Fluo-8 are cleaved by an esterase, resulting in a negatively charged fluorescent dye that stays inside the cell. Its fluorescence is greatly enhanced upon binding to calcium. When cells are stimulated with agonists, the receptor signals the release of intracellular calcium, which significantly increases the fluorescence of Fluo-8. The characteristics of its long wavelength, high sensitivity, and >100 times fluorescence enhancement make Fluo-8 the brightest green calcium indicator available in the marker, and it is an ideal tool for the measurement of cellular calcium through HTS screening. The kit provides an optimized assay method for monitoring the G-protein-coupled receptors and calcium channels using HTS instrumentation. The assay can be performed in a convenient 96-well or 384-well microtiter-plate format. http://www.creativebiomart.net/Fluo-8-No-Wash-Calcium-Assay-kit-462850.htm
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About our Company

Business Type
Manufacturer
Established
2005
Employess
51 - 100 People
Annual Revenue
US$10 Million - US$50 Million
Main Markets
North America, Eastern Europe, East Asia, South America, Southern Europe, South Asia, Central America, Western Europe
Export Ratio
21% - 30%
Products
Pharmaceuticals

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Pharmaceuticals in USA

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Ms. Linna Green

USA

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