Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)

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Model Number: GR1902
Brand Name: Creative Peptides
Place of Origin: USA
MOQ: 1

Product Detail

This is a peptide derived from rabies virus glycoprotein (RVG). Because neurotropic viruses cross the blood-brain barrier to infect brain cells, the same strategy may be used to enter the central nervous system and deliver siRNA to the brain. To enable siRNA binding, this chimeric peptide was synthesized by adding nonamer arginine residues at the carboxy terminus of RVG. This RVG-9R peptide was able to bind and transduce siRNA to neuronal cells in vitro, resulting in efficient gene silencing. After intravenous injection into mice,RVG-9R delivered siRNA to the neuronal cells, resulting in specific gene silencing within the brain. RVG-9R provides a safe and noninvasive approach for the delivery of siRNA and potentially other therapeutic molecules across the blood–brain barrier.
Mr. Cathy Miller
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About our Company

Business Type
51 - 100 People
Annual Revenue
US$5 Million - US$10 Million
Main Markets
North America, Eastern Europe, East Asia, Africa, South America, Southern Europe, South Asia, Oceania, Central America, Western Europe, Middle East
Export Ratio
31% - 40%

Regional Suppliers

Biochemicals in USA

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Creative Peptides

Mr. Cathy Miller

45-16 Ramsey Road Shirley

New York New York 11967 USA

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